Wires is a slang term used by Mercury and others to nickname radio transmissions. Because there is no such thing as never getting chased after, people like Merc must hear radio reports from City Protection Force to know what they're planning to do. When hearing these and knowing what they're going to do, the helpers can warn Runners where to go and not to go, including where enemies can be blocking the way.
While in game, wires aren't used by Faith Connors, with the exception of "Flight" cutscene where she overhears her sister, and in the chapter "Kate", where Merc connected her earpiece to the wires. Instead, Merc act as a guide and uses the wires as an advantage along with schematics of the location.